COUMARIN (Anticancerous Drug)

Coumarins, a fused benzene and pyrone ring systems are of growing importance as targets for synthesis.
It plays an important place in drug discovery process due to its presence in diversity of biologically active compounds.
It has a tremendous ability to regulate diverse range of cellular pathways that can be explored for selective anticancer activity, antibacterial and antifungal activity.
A new area of research and prompted authors to compile literature on its synthesis and improved biological properties. Antibacterial and antifungal are the very serious problem nowadays, and many drugs are available for this kind of treatment.
Coumarin is used in certain perfumes and fabric conditioners.
Due to development of Candida pathogens, the search is still on to develop drugs for specific types of disease.
In present work Synthesis and characterisation of 10 coumarin derivatives has been done. These compounds will be analysed for their Antibacterial and Antifungal activity on various cell lines.
Coumarin has been used as an aroma enhancer in pipe tobaccos and certain alcoholic drinks, although in general it is banned as a flavorant food additive, due to concerns regarding its hepatotoxicity in animal models.